UEFA Nations League 2021: Italy vs Spain Prediction and Odds: Italy to Win

Host Italy is predicted to win against Spain in the upcoming UEFA Nations League semi-finals as per the latest Italy vs Spain Prediction and Odds

Italy and Spain set to renew their rivalries in the UEFA Nations League at the iconic San Siro. The Azzuri are flying high following their European Championship triumph back in July. Roberto Mancini’s men defeated England in penalties to lift their first trophy in the Mancini era.

Spain’s Euro journey too ended at the hands of Italy as the La Roja saw their Euro dreams crashed following a penalty shootout defeat to the men in blue.

Luis Enrique’s men will now be aiming to avenge their defeat when they travel to Italy.

Italy vs Spain Prediction and Odds

Italy vs Spain Prediction and Odds: Predicted Winner

Italy and Spain are set to meet in the first semi-final of Nations League 2021 on Wednesday at San Siro, a nickname for the Stadio Giuseppe Meazza football stadium in the San Siro district of Milan, Italy. The host team, Italy enjoys the home advantage. Added to it, Italy has had a better recent form as compared to that of Spain.

Looking at the recent form and also considering the home advantage, Italy is predicted to win against Spain in the first UEFA Nations League 2021 semi-finals. The latest Italy vs Spain Prediction and Odds also predicts a win for the host team, Italy.

Euro 2020 SF Highlights: Italy beat Spain 4-2 on penalties to reach final,  Spain knocked out | Hindustan Times

Italy vs Spain Match Odds

ItalySpainPredicted winner
PaddypowerOdds: 2.25Odds: 3.30Italy
SmarketsWin Probability: 42.02%Win Probability: 27.03%Italy
BetwayOdds: 2.30Odds: 3.30Italy

All the Italy vs Spain Prediction and Odds are predicting Italy’s win over Spain in the UEFA Nations League semifinal.

Italy vs Spain Prediction and Odds: Preview

Mancini called up a squad of 23 players but with a number of players already injured the former Manchester City manager has been forced to call in some replacements.

Goalkeepers: Gianluigi Donnarumma (Paris Saint Germain), Alex Meret (Napoli), Salvatore Sirigu (Genoa)

Defenders: Francesco Acerbi (Lazio), Alessandro Bastoni (Inter), Leonardo Bonucci (Juventus), Giorgio Chiellini (Juventus), Giovanni Di Lorenzo (Napoli), Emerson Palmieri (Lyon), Rafael Toloi (Atalanta)

Midfielders: Nicolò Barella (Inter), Bryan Cristante (Roma), Jorginho (Chelsea), Manuel Locatelli (Juventus), Lorenzo Pellegrini (Roma), Matteo Pessina (Atalanta), Marco Verratti (Paris Saint Germain)

Forwards: Domenico Berardi (Sassuolo), Federico Bernardeschi (Juventus), Federico Chiesa (Juventus), Ciro Immobile (Lazio), Lorenzo Insigne (Napoli), Giacomo Raspadori (Sassuolo).

Moise Kean and Davide Calabria have already replaced Immobile and Rafael Toloi respectively.

It has also been reported that injured Matteo Pessina could be replaced by AC Milan midfielder Sandro Tonali.

Spain too has faced similar issues as Enrique also called in some reinforcements.

Goalkeepers: Unai Simon, David de Gea, Robert Sanchez.

Defenders: Cesar Azpilicueta, Pedro Porro, Eric Garcia, Pau Torres, Aymeric Laporte, Inigo Martinez, Sergio Reguilon, Marcos Alonso.

Midfielders: Sergio Busquets, Rodri Hernandez, Pedri, Mikel Merino, Koke, Gavi, Marcos Llorente, Pablo Fornals.

Forwards: Ferran Torres, Pablo Sarabia, Mikel Oyarzabal, Yeremi Pino.

Pedri withdrew his name from the squad and Celta Vigo’s Brais Mendez has replaced him.

Marcos Llorente also pulled out for an injury and Tottenham Hotspur’s Bryan Gil has joined the squad in his place.

Like in the European Championship Enrique felt to Real Madrid players capable of playing in his team and thus for the second time in a row he decided not to call any players from Los Blancos.

Italy is also hosting the other semifinal France vs Belgium in Turin and the final will also be played at the San Siro on 10th October. The Azzuri are currently on a 27 game unbeaten run and are tipped to be the favorites to lift the trophy on their home soil.

With all the potential attackers currently out on the sidelines, Enrique will only have the luxury to use Alvaro Morata and Mikel Oyarzabal as a false nine as it stands.

Ander Herrera and Brahim Diaz were expected to get a call-up but they were ignored.

Barring Keane, Calabria, Tonali, and Pellegrini the rest of the squad remains the same which lifted the European Championship trophy at Wembley.

Italy vs Spain Prediction and Odds: Predicted Lineup


Gianluigi Donnarumma became the Italian hero as he saved Bukayo Saka’s penalty in the European Championship final to send his country into sheer joy.

Giorgio Chiellini and Leonardo Bonucci will start in the heart of the defence.

Emerson and Giovanni Di Lorenzo will be the two side backs.

The three man midfield will be manned by Jorginho, Nicolo Barella and Marco Verratti.

Moise Kean, Federico Chiesa and Lorenzo Insigne will be the front three attackers.


Given David De Gea’s recent form he should be the preferred choice in the Spain goal.

Aymeric Laporte will partner Pau Torres in the Spanish backline.

Sergio Reguilon and Cesar Azpilicueta will start as the two side-backs.

Sergio Busquets, Carlos Soler, and Koke will star in the midfield.

Pablo Fornals, Ferran Torres, and Olazabal will be the front three.

Italy vs Spain H2H

The Mediterranean derby or Italy vs Spain rivalry has been highly interesting as of now. The two teams have played a total of 38 international head-to-head matches as of now. Of 38 matches, Italy has 11 wins and even Spain also has 11 victories over Italy. 16 matches between the two teams have ended in a draw.

In the last five matches between the two teams, 2 matches ended in a draw. Italy has won 2 of the last 5 matches against Spain while Spain has just one victory.

The last match between the two teams ended in a draw in regular timing. Italy won the match in penalties.

Italy vs Spain1-1UEFA European ChampionshipItaly(won on penalties)
Spain vs Italy3-0FIFA World CupSpain
Italy vs Spain1-1FIFA World CupDraw
Italy vs Spain2-0UEFA European ChampionshipItaly
Italy vs Spain1-1International FriendlyDraw
Spain vs Italy1-0International FriendlySpain
Spain vs Italy0-0FIFA Confederations CupSpain
Spain vs Italy4-0UEFA European ChampionshipSpain
Spain vs Italy1-1UEFA European ChampionshipDraw

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Subhash, Founder of Crowdwisdom360 is an MBA and a Trained Financial Advisor with an extensive background in Forecasting in Financial Services and Politics. He has appeared many times on National TV and has written for a variety of magazines on Wealth Management and Election Strategy.

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